The final chapter...finally

I had blood drawn for another beta yesterday morning and received the call from the nurse at around 8 pm last night, which was worrisome in itself because it's way outside their normal business hours. My number increased from 494 to 1955 in six days. The beta is high enough at this point that if there were anything viable in the uterus, they would have seen it. She asked me to come in again this morning, and was again very adamant that if I have any pain, especially on one side or the other, I was to go to the emergency room immediately.

I had some severe cramping (exactly like period cramps and not on one side or the other) for a couple of hours around dinner time last night, and started bleeding bright red. The cramps and bleeding tappered off around 7 pm (just before she called) and I got a decent sleep, thankfully. I arrived at the clinic this morning shortly after 9 am and they sent me right to the clinic for another beta and a bunch of labs for liver function. The purpose of the liver function tests was that if my beta had continued to increase, I'd have to go in for a methotexrate shot to stop the development of whatever it is, wherever it is, and the shot can harm poorly functioning livers.

Unfortunately, my beta this morning increased to 2100, so we have an appointment this evening at 6:30 at the hospital to get the shot.

Just to clear up some confusion about why I am getting the shot even though it seems like something is developing still, I'll try to explain a few things. In a normal pregnancy, the beta will go up about 66% every 48 to 72 hours for the first few weeks. 85% of women follow this guideline, but 15% do not. I was close for a few of my beta's, which is why I held on to the hope that I was part of that 15%. My initial beta of 24 at about 13 days past ovulation was low, but you have to start somewhere, and I was hoping it just implanted late. I also didn't know the exact date of ovulation, so I could have been even earlier, and there the justification for my low numbers began.

So, my numbers would almost double, not double, almost double, not double, etc., but keep going up. However, they weren't going up fast enough. My beta yesterday of 1955 was taken on a day where I was at very earliest (according to my justifications) six weeks two days pregnant, and at latest, six weeks six days pregnant. The normal beta range for six weeks zero days is between 1080 and 56,500 mIU. I was in range, but barely.

After my beta this morning of 2100, things were essentially confirmed. A rise of only 150-ish in 24 hours is a failed pregnancy.

I have no question that this isn't viable at this point. If I stop trying to justify everything and make my numbers work, I'd be seven weeks today, and nothing is supporting that - beta numbers or ultrasound.

The good news is that this chapter is finally coming to a close and the next chapter is beginning. We are still on the list for the September IVF / Donor Egg seminars which means we're still on schedule for a December / January IVF. This threw a wrench in to the machine, but luckily it wasn't a big wrench.

Still on the roller coaster

Just a quick update from the last post - unfortunately, my hopes were once again recharged following my sixth beta. Three days after my poor beta of 229, I had a repeat and was shocked to hear that it had increased to 494! Hope springs eternal and all that!

I received the results last Friday and we were cautiously optomistic all weekend. I purchased a CBE with Conception Indicator pregnancy test the afternoon I received these awesome results and it showed that I was 2 - 3 weeks pregnant, which was low for where I was in the pregnancy according to my last period, but I justified the numbers away and hoped for the best.

On Monday (yesterday), I took yet another CBE with Conception Indicator and it had jumped to 3+ weeks pregnant! My beta was going up! According to some random information I found online, for the test to read 3+ weeks, my beta would have to be over 1000 or so. Exciting! I was hopeful that we might actually see a little bean on my ultrasound this morning.

But, it was not to be. While we did get the good news that they didn't see anything in my tubes, and therefore my risk for ectopic was 'very low', we also didn't see anything in my uterus. Based upon my chart, which shows when we had sex and when I got my first positive pregnancy test, the earliest I could be is about 6 weeks, 2 days, and the clinic has me down as 6 weeks, 6 days. Either way, there should have been something. All they saw was a nice thick endometrium and that's it.

The doctor sent me for another beta and I should have the results by the end of today, but of course, when I finally got to work around noon, I started cramping and finally started spotting red. I think it's finally over and the numbers from this morning will prove it.

Being on this emotional roller coaster has caused so much stress for me, Derek and our families (especially my sister Lara, who is waiting for me to donate eggs to her - this puts her life on hold as well) that I'll be thankful to conclude this chapter in our lives.

It's officially loss number three

The clinic called late yesterday afternoon and told me my number had only gone up to 229 from 180, a rise of only 21%. About three hours before they called, I started spotting, so I already knew it was over.

Thank you everyone for all your support and positive thoughts, but it looks like this one is coming to an end too. At this point, I am hoping for a quick natural miscarriage.

Going forward, we'll be making an appointment to see both our IVF doctor and the Repeat Pregnancy Loss doctor at the fertility clinic to discuss what the plan is going forward. On the positive side of this all, we will be doing more investigation to determine if there is something genetic going on with us, or if there is something going on in my uterus that is preventing good implantation. I'm glad we'll be doing this before the IVF rather then going through more heartbreak and big costs, though we have to be realistic, as there is only a 50% chance that we will find an answer.

For now, we're both dealing with this pretty well. It's obviously different for Derek because he isn't the one that's pregnant and it wasn't to the point of being real for him yet, but I'm sure he's sad about this too. Staying positive about the future is what keeps us going, and knowing that we have a good plan is reassuring.